Week 4 of college football features a series of highly anticipated matchups, such as the Michigan-Iowa game and the Oregon-USC contest. This week is noted for having the highest number of ranked games since 2023. Predictions and betting lines are available for the top 25 matchups. Live updates, schedules, and scores are tracked on NCAA.com. Donald Trump was present at a game with a plan to protect communications. Live broadcasts are available on SiriusXM and local stations.